<i>Creative Confluence</i> is a highly original work, building bridges between physics, biology, technology, economy, organizations, neuropsychology, literature, arts, and cultural history. It is an attempt to explain the process of creativity as a universal principle of nature, cutting through the composition of atoms as well as human design of novel combinations. <i>Creative Confluence</i> is yet another impressive book and a sequel to <i>Epistemics of the Virtual</i>, indicating that perception and imagination operate in close contact. In a clear and light tone, the work holds that rational problem-solving strategies are most relevant in deterministic problem spaces whereas creativity is pertinent in more probabilistic situations. Theories of creativity and innovation are explored by means of computer simulations. Conditionals that favor creativity such as diversity, tolerance, and openness are discussed, forwarding a compelling vision of creative leadership.